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Academic Journal

Associations Between Genetically Predicted Protein Levels and COVID-19 Severity.

Subjects: COVID-19; FALSE discovery rate; SARS-CoV-2

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p19-22. 4p.

  • Abstract: It is critical to identify potential causal targets for SARS-CoV-2, which may guide drug repurposing options. We assessed the associations between ...

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Academic Journal

The Issue of Recurrently Positive Patients Who Recovered From COVID-19 According to the Current Discharge Criteria: Investigation of Patients from Multiple Medical Institutions in Wuhan, China.

Subjects: COVID-19; REVERSE transcriptase polymerase chain reactionWUHAN (China)

  • Source: Journal of Infectious Diseases. Dec2020, Vol. 222 Issue 11, p1784-1788. 5p.

  • Abstract: The current discharge criteria for COVID-19 require that patients have 2 consecutive negative results for reverse transcription polymerase chain reaction (RT-PCR) detection. ...

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Academic Journal

Definition and Risks of Cytokine Release Syndrome in 11 Critically Ill COVID-19 Patients With Pneumonia: Analysis of Disease Characteristics.

Subjects: *CYTOKINE release syndrome; *COVID-19; *CRITICALLY illCHINA

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1444-1451. 8p.

  • Abstract: Corona virus disease 2019 (COVID-19) patients with severe immune abnormalities are at risk of cytokine release syndrome (CRS). The definition, prevention, and ... Copyright of Journal of Infectious Diseases is the property of Oxford University Press / USA and its content may not be ...

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Academic Journal

COVID-19 Vaccines: Should We Fear ADE?

Subjects: COVID-19 vaccines; COVID-19; RESPIRATORY syncytial virus

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1946-1950. 5p.

  • Abstract: Might COVID-19 vaccines sensitize humans to antibody-dependent enhanced (ADE) breakthrough infections? This is unlikely because coronavirus diseases ...

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Academic Journal

Plasma From Recovered COVID-19 Patients Inhibits Spike Protein Binding to ACE2 in a Microsphere-Based Inhibition Assay.

Subjects: CARRIER proteins; COVID-19; ANGIOTENSIN converting enzyme

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1965-1973. 9p.

  • Abstract: We present a microsphere-based flow cytometry assay that quantifies the ability of plasma to inhibit the binding of spike protein to angiotensin-converting enzyme 2. Plasma from 22 ...

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Academic Journal

Nonpharmaceutical Interventions Used to Control COVID-19 Reduced Seasonal Influenza Transmission in China.

Subjects: SEASONAL influenza; COVID-19; COVID-19 pandemicCHINA

  • Source: Journal of Infectious Diseases. Dec2020, Vol. 222 Issue 11, p1780-1783. 4p.

  • Abstract: To suppress the ongoing COVID-19 pandemic, the Chinese government has implemented nonpharmaceutical interventions (NPIs). Because COVID-19 and ...

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Academic Journal

COVID-19 Pandemic: Disparate Health Impact on the Hispanic/Latinx Population in the United States.

Subjects: COVID-19 pandemic; HISPANIC Americans; COVID-19WUHAN (China); UNITED States

  • Source: Journal of Infectious Diseases. 11/15/2020, Vol. 222 Issue 10, p1592-1595. 4p.

  • Abstract: In December 2019, a novel coronavirus known as SARS-CoV-2, emerged in Wuhan, China, causing the ...

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Academic Journal

Ethical Implementation of Immunity Passports During the COVID-19 Pandemic.

Subjects: COVID-19 pandemic; PUBLIC health ethics; PASSPORTS

  • Source: Journal of Infectious Diseases. 9/1/2020, Vol. 222 Issue 5, p715-718. 4p.

  • Abstract: A number of countries are planning the use of "immunity passports" as a way to ease restrictive measures and allow infected and recovered people to ...

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Academic Journal

Neutralizing Antibody Responses in COVID-19 Convalescent Sera.

Subjects: CONVALESCENT plasma; COVID-19; ANTIBODY formationUNITED States

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p47-55. 9p.

  • Abstract: Passive transfer of antibodies from COVID-19 convalescent patients is being used as an experimental treatment for eligible patients with

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Academic Journal

A Granulocytic Signature Identifies COVID-19 and Its Severity.

Subjects: COVID-19; BIOMARKERS; INTENSIVE care units

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1985-1996. 12p.

  • Abstract: Background: An unbiased approach to SARS-CoV-2-induced immune dysregulation has not been undertaken so far. We aimed to identify ...

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Academic Journal

Postmortem Findings in Italian Patients With COVID-19: A Descriptive Full Autopsy Study of Cases With and Without Comorbidities.

Subjects: COVID-19; AUTOPSY; POSTMORTEM changesROME

  • Source: Journal of Infectious Diseases. Dec2020, Vol. 222 Issue 11, p1807-1815. 9p.

  • Abstract: Background: Descriptions of the pathological features of coronavirus disease-2019 (COVID-19) caused by the novel zoonotic ...

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Academic Journal

Convalescent Plasma Therapy in Patients With Severe or Life-Threatening COVID-19: A Metadata Analysis.

Subjects: *COVID-19; *METADATA; *PATIENTS

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1575-1578. 4p.

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Academic Journal

The Importance of Cellular Immunity in the Development of Vaccines and Therapeutics for COVID-19.

Subjects: *COVID-19; *CELLULAR immunity; *THERAPEUTICS

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1435-1438. 4p.

  • Abstract: It is important to develop vaccines that can also mediate T-cell responses to SARS-CoV-2 to limit severity of infections, and to ... Copyright of Journal of Infectious Diseases is the property of Oxford University Press / USA and its content may not be ...

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Academic Journal

SARS-CoV-2 Antibody Avidity Responses in COVID-19 Patients and Convalescent Plasma Donors.

Subjects: CONVALESCENT plasma; COVID-19; SARS-CoV-2

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1974-1984. 11p.

  • Abstract: Background: Convalescent plasma therapy is a leading treatment for conferring temporary immunity to COVID-19-susceptible individuals or for use ...

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Academic Journal

The Case for Why Africa Should Host COVID-19 Candidate Vaccine Trials.

Subjects: VACCINE trials; COVID-19; WORLD Health OrganizationAFRICA

  • Source: Journal of Infectious Diseases. Aug2020, Vol. 222 Issue 3, p351-355. 5p.

  • Abstract: In response to provocative comments by 2 European clinicians and scientists, the World Health Organization Director General has declared that Africa will not host

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Academic Journal

Paying Participants in COVID-19 Trials.

Subjects: COVID-19; CLINICAL trials; COVID-19 treatment

  • Source: Journal of Infectious Diseases. Aug2020, Vol. 222 Issue 3, p356-361. 6p.

  • Abstract: Trials are in development and underway to examine potential interventions for treatment and prophylaxis of coronavirus disease 2019 (COVID-19

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Academic Journal

Persistent COVID-19 in an Immunocompromised Patient Temporarily Responsive to Two Courses of Remdesivir Therapy.

Subjects: COVID-19; REMDESIVIR; IMMUNOCOMPROMISED patients

  • Source: Journal of Infectious Diseases. 10/1/2020, Vol. 222 Issue 7, p1103-1107. 5p.

  • Abstract: The antiviral drug remdesivir has been shown clinically effective for treatment of COVID-19. We here demonstrate suppressive but not curative effect ...

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Academic Journal

Environmental Sampling for Severe Acute Respiratory Syndrome Coronavirus 2 During a COVID-19 Outbreak on the Diamond Princess Cruise Ship.

Subjects: COVID-19 pandemic; ENVIRONMENTAL sampling; COVID-19

  • Source: Journal of Infectious Diseases. 10/1/2020, Vol. 222 Issue 7, p1098-1102. 5p.

  • Abstract: During a COVID-19 outbreak on the Diamond Princess cruise ship we sampled environmental surfaces after passengers and crew vacated cabins.

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Academic Journal

Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results.

Subjects: COVID-19; DIAGNOSIS methods; GOLD standard

  • Source: Journal of Infectious Diseases. 9/15/2020, Vol. 222 Issue 6, p899-902. 4p.

  • Abstract: False-negative severe acute respiratory syndrome coronavirus 2 test results can negatively impact the clinical and public health response to ...

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Academic Journal

Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients.

Subjects: CELL adhesion molecules; COVID-19; ENDOTHELIAL cellsCHINA

  • Source: Journal of Infectious Diseases. 9/15/2020, Vol. 222 Issue 6, p894-898. 5p.

  • Abstract: In a retrospective study of 39 COVID-19 patients and 32 control participants in China, we collected clinical data and examined the expression of ...

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Academic Journal

Elevation of Liver Fibrosis Index FIB-4 Is Associated With Poor Clinical Outcomes in Patients With COVID-19.

Subjects: COVID-19; CARDIOVASCULAR diseases risk factors; FIBROSIS

  • Source: Journal of Infectious Diseases. 9/1/2020, Vol. 222 Issue 5, p726-733. 8p.

  • Abstract: Background: COVID-19 is a potentially severe disease caused by the recently described SARS-CoV-2. Whether liver ...

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Academic Journal

ACE2 Expression Is Increased in the Lungs of Patients With Comorbidities Associated With Severe COVID-19.

Subjects: COVID-19; OBSTRUCTIVE lung diseases; ANGIOTENSIN converting enzyme

  • Source: Journal of Infectious Diseases. 8/15/2020, Vol. 222 Issue 4, p556-563. 8p.

  • Abstract: Patients who died from COVID-19 often had comorbidities, such as hypertension, diabetes, and chronic obstructive lung disease. Although angiotensin-converting enzyme 2 (ACE2) ...

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Academic Journal

Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia.

Subjects: COVID-19; LYMPHOCYTE subsets; T cellsWUHAN (China); CHINA

  • Source: Journal of Infectious Diseases. 06/01/2020, Vol. 221 Issue 11, p1762-1769. 8p.

  • Abstract: Background: In December 2019, novel coronavirus (SARS-CoV-2) pneumonia (COVID-19) was reported in ...

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Academic Journal

Effect of Convalescent Plasma Therapy on Viral Shedding and Survival in Patients With Coronavirus Disease 2019.

Subjects: COVID-19; VIRAL shedding; CORONAVIRUS diseases

  • Source: Journal of Infectious Diseases. 7/1/2020, Vol. 222 Issue 1, p38-43. 6p.

  • Abstract: Currently, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (

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Academic Journal

A 55-Day-Old Female Infant Infected With 2019 Novel Coronavirus Disease: Presenting With Pneumonia, Liver Injury, and Heart Damage.

Subjects: COVID-19; CORONAVIRUS diseases; LIVER injuriesCHINA

  • Source: Journal of Infectious Diseases. 06/01/2020, Vol. 221 Issue 11, p1775-1781. 7p.

  • Abstract: Background: Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were ...

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Academic Journal

Findings From a Probability-Based Survey of United States Households About Prevention Measures Based on Race, Ethnicity, and Age in Response to Severe Acute Respiratory Syndrome Coronavirus 2.

Subjects: COVID-19; COVID-19 pandemic; SARS-CoV-2UNITED States

  • Source: Journal of Infectious Diseases. 11/15/2020, Vol. 222 Issue 10, p1607-1611. 5p.

  • Abstract: We investigated individual behaviors taken by white, African American, and Latino United States (US) households in response to severe acute respiratory syndrome ...

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Academic Journal

A High-Throughput Assay for Circulating Antibodies Directed Against the S Protein of Severe Acute Respiratory Syndrome Coronavirus 2.

Subjects: COVID-19; COVID-19 pandemic; CORONAVIRUS diseases

  • Source: Journal of Infectious Diseases. 11/15/2020, Vol. 222 Issue 10, p1629-1634. 6p.

  • Abstract: More than 24 million infections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were confirmed globally by September 2020. ...

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Academic Journal

SARS-CoV-2–Specific Antibody Detection for Seroepidemiology: A Multiplex Analysis Approach Accounting for Accurate Seroprevalence.

Subjects: COVID-19 pandemic; SARS-CoV-2; SEROPREVALENCE

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1452-1461. 10p.

  • Abstract: Background The COVID-19 pandemic necessitates better understanding of the kinetics of antibody production induced by infection with SARS-CoV-2

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Academic Journal

Interferon-β-1a Inhibition of Severe Acute Respiratory Syndrome-Coronavirus 2 In Vitro When Administered After Virus Infection.

Subjects: VIRUS diseases; COVID-19; INTERFERON beta-1a

  • Source: Journal of Infectious Diseases. 9/1/2020, Vol. 222 Issue 5, p722-725. 4p.

  • Abstract: The ongoing coronavirus disease 2019 pandemic has forced the clinical and scientific community to try drug repurposing of existing antiviral agents as ...

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Academic Journal

Analysis of Humoral Immune Responses in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

Subjects: COVID-19; UNIVERSITY of Colorado Hospital; HUMORAL immunityFRANKFURT am Main (Germany)

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p56-61. 6p.

  • Abstract: Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused a pandemic with tens ...

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Academic Journal

Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 Replication in an Immunocompromised Patient.

Subjects: COVID-19; CONVALESCENT plasma; IMMUNOCOMPROMISED patients

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p23-27. 5p.

  • Abstract: We describe a case of chronic coronavirus disease 2019 (COVID-19) in a patient with lymphoma and associated B-cell ...

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Academic Journal

CoVA: An Acuity Score for Outpatient Screening that Predicts Coronavirus Disease 2019 Prognosis.

Subjects: COVID-19; PROGNOSIS; OXYGEN in the blood

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p38-46. 9p.

  • Abstract: Background: We sought to develop an automatable score to predict hospitalization, critical illness, or death for patients at risk for ...

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Academic Journal

Upper Respiratory Tract Levels of Severe Acute Respiratory Syndrome Coronavirus 2 RNA and Duration of Viral RNA Shedding Do Not Differ Between Patients With Mild and Severe/Critical Coronavirus Disease 2019.

Subjects: COVID-19; VIRAL shedding; VIRAL load

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p15-18. 4p.

  • Abstract: This study reports longitudinal viral RNA loads from the nasopharynx/throat in patients with mild and severe/critical coronavirus disease 2019 (

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Academic Journal

Clinical Presentation and Outcomes of Severe Acute Respiratory Syndrome Coronavirus 2-Related Encephalitis: The ENCOVID Multicenter Study.

Subjects: SARS (Disease); COVID-19; ENCEPHALITISITALY

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p28-37. 10p.

  • Abstract: Background: Several preclinical and clinical investigations have argued for nervous system involvement in severe acute respiratory syndrome coronavirus 2 (

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Academic Journal

Location Matters: Geographic Disparities and Impact of Coronavirus Disease 2019.

Subjects: COVID-19; PANDEMICS; AGE groupsUNITED States

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1951-1954. 4p.

  • Abstract: The coronavirus disease 2019 (COVID-19) pandemic in the United States has revealed major disparities in the access to ...

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Academic Journal

Circulating Endothelial Cells as a Marker of Endothelial Injury in Severe COVID -19.

Subjects: ENDOTHELIAL cells; COVID-19; INTENSIVE care patients

  • Source: Journal of Infectious Diseases. Dec2020, Vol. 222 Issue 11, p1789-1793. 5p.

  • Abstract: Beside the commonly described pulmonary expression of the coronavirus disease 2019 (COVID-19), major vascular events have been reported. ...

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Academic Journal

Cluster of Severe Acute Respiratory Syndrome Coronavirus 2 Infections Linked to Music Clubs in Osaka, Japan.

Subjects: CORONAVIRUS diseases; COVID-19; MUSIC associationsOSAKA (Japan)

  • Source: Journal of Infectious Diseases. 11/15/2020, Vol. 222 Issue 10, p1635-1640. 6p.

  • Abstract: Background: It is important to understand the mode of transmission of severe acute respiratory syndrome coronavirus 2 (...

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Academic Journal

Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Antibody Titers in Convalescent Plasma and Recipients in New Mexico: An Open Treatment Study in Patients With Coronavirus Disease 2019.

Subjects: COVID-19; UNITED States. Food & Drug Administration; CORONAVIRUS diseasesNEW Mexico

  • Source: Journal of Infectious Diseases. 11/15/2020, Vol. 222 Issue 10, p1620-1628. 9p.

  • Abstract: Background: Convalescent plasma (CP) is a potentially important therapy for coronavirus disease 2019 (COVID-19). However, knowledge ...

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Academic Journal

Immunoserologic Detection and Diagnostic Relevance of Cross-Reactive Autoantibodies in Coronavirus Disease 2019 Patients.

Subjects: COVID-19; AUTOANTIBODIES; GASTRIC mucosa

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1439-1443. 5p.

  • Abstract: Background During the coronavirus disease 2019 (COVID-19) pandemic, we detected a new immunofluorescence (IF) pattern in serum autoantibody (...

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Academic Journal

Evaluation of Serological Tests for SARS-CoV-2: Implications for Serology Testing in a Low-Prevalence Setting.

Subjects: SARS-CoV-2; COVID-19 pandemic; COVID-19AUSTRALIA

  • Source: Journal of Infectious Diseases. 10/15/2020, Vol. 222 Issue 8, p1280-1288. 9p.

  • Abstract: Background: Robust serological assays are essential for long-term control of the COVID-19 pandemic. Many recently released point-of-care (PoCT) serological ...

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Academic Journal

Estimation Without Representation: Early Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Studies and the Path Forward.

Subjects: COVID-19; COVID-19 pandemic; SEROPREVALENCE

  • Source: Journal of Infectious Diseases. 10/1/2020, Vol. 222 Issue 7, p1086-1089. 4p.

  • Abstract: The recent development and regulatory approval of a variety of serological assays indicating the presence of antibodies against severe acute respiratory syndrome ...

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Academic Journal

SARS-CoV-2 Seroprevalence and Antibody Kinetics Among Health Care Workers in a Spanish Hospital After 3 Months of Follow-up.

Subjects: MEDICAL personnel; SARS-CoV-2; SEROPREVALENCESPAIN

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p62-71. 10p.

  • Abstract: Background: At the COVID-19 spring 2020 pandemic peak in Spain, prevalence of SARS-CoV-2 infection in a ...

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Academic Journal

High Seroprevalence of Anti-SARS-CoV-2 Antibodies in Chelsea, Massachusetts.

Subjects: CHELSEA; SEROPREVALENCE; SERODIAGNOSISMASSACHUSETTS

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1955-1959. 5p.

  • Abstract: SARS-CoV-2 antibody testing allows quantitative determination of disease prevalence, which is especially important in high-risk communities. We performed anonymized convenience sampling ...

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Academic Journal

Environmental and Aerosolized Severe Acute Respiratory Syndrome Coronavirus 2 Among Hospitalized Coronavirus Disease 2019 Patients.

Subjects: COVID-19; SARS-CoV-2

  • Source: Journal of Infectious Diseases. Dec2020, Vol. 222 Issue 11, p1798-1806. 9p.

  • Abstract: During April and May 2020, we studied 20 patients hospitalized with coronavirus disease 2019 (COVID-19), their hospital rooms (fomites and ...

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Academic Journal

Coronavirus Disease 2019 Epidemic Doubling Time in the United States Before and During Stay-at-Home Restrictions.

Subjects: COVID-19; STAY-at-home orders; CORONAVIRUS diseasesUNITED States

  • Source: Journal of Infectious Diseases. 11/15/2020, Vol. 222 Issue 10, p1601-1606. 6p.

  • Abstract: Background: Coronavirus disease 2019 (COVID-19) has spread rapidly in the United States since January 2020.Methods:

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Academic Journal

Transient Lymphopenia and Interstitial Pneumonia With Endotheliitis in SARS-CoV-2-Infected Macaques.

Subjects: COVID-19; PULMONARY fibrosis; MACAQUES

  • Source: Journal of Infectious Diseases. 11/15/2020, Vol. 222 Issue 10, p1596-1600. 5p.

  • Abstract: Using a reliable primate model is critical for developing therapeutic advances to treat humans infected with severe acute respiratory syndrome coronavirus...

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Academic Journal

Methods of Inactivation of SARS-CoV-2 for Downstream Biological Assays.

Subjects: SARS-CoV-2; COVID-19; BIOLOGICAL assay

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1462-1467. 6p.

  • Abstract: The scientific community has responded to the coronavirus disease 2019 (COVID-19) pandemic by rapidly undertaking research to find ...

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Academic Journal

Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study.

Subjects: COVID-19; SYMPTOMS; CHINA studies

  • Source: Journal of Infectious Diseases. 10/15/2020, Vol. 222 Issue 8, p1293-1297. 5p.

  • Abstract: The number of coronavirus disease 2019 (COVID-19) cases has exceeded 10 million. However, little is known about the epidemiology ...

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Academic Journal

Differences in Antibody Kinetics and Functionality Between Severe and Mild Severe Acute Respiratory Syndrome Coronavirus 2 Infections.

Subjects: COVID-19; CORONAVIRUS diseases; IMMUNOGLOBULIN G

  • Source: Journal of Infectious Diseases. 10/15/2020, Vol. 222 Issue 8, p1265-1269. 5p.

  • Abstract: We determined and compared the humoral immune response in patients with severe (hospitalized) and mild (nonhospitalized) coronavirus disease 2019 (...

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Academic Journal

Global Seasonality of Human Seasonal Coronaviruses: A Clue for Postpandemic Circulating Season of Severe Acute Respiratory Syndrome Coronavirus 2?

Subjects: COVID-19; COVID-19 pandemic; CORONAVIRUS diseasesCHINA

  • Source: Journal of Infectious Diseases. 10/1/2020, Vol. 222 Issue 7, p1090-1097. 8p.

  • Abstract: Background: The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome

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