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Academic Journal

Convalescent Plasma Therapy in Patients With Severe or Life-Threatening COVID-19: A Metadata Analysis.

Subjects: *COVID-19; *METADATA; *PATIENTS

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1575-1578. 4p.

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Academic Journal

The Importance of Cellular Immunity in the Development of Vaccines and Therapeutics for COVID-19.

Subjects: *COVID-19; *CELLULAR immunity; *THERAPEUTICS

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1435-1438. 4p.

  • Abstract: It is important to develop vaccines that can also mediate T-cell responses to SARS-CoV-2 to limit severity of infections, and to ... Copyright of Journal of Infectious Diseases is the property of Oxford University Press / USA and its content may not be ...

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Academic Journal

Definition and Risks of Cytokine Release Syndrome in 11 Critically Ill COVID-19 Patients With Pneumonia: Analysis of Disease Characteristics.

Subjects: *CYTOKINE release syndrome; *COVID-19; *CRITICALLY illCHINA

  • Source: Journal of Infectious Diseases. Nov2020, Vol. 222 Issue 9, p1444-1451. 8p.

  • Abstract: Corona virus disease 2019 (COVID-19) patients with severe immune abnormalities are at risk of cytokine release syndrome (CRS). The definition, prevention, and ... Copyright of Journal of Infectious Diseases is the property of Oxford University Press / USA and its content may not be ...

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Academic Journal

Neutralizing Antibody Responses in COVID-19 Convalescent Sera.

Subjects: CONVALESCENT plasma; COVID-19; ANTIBODY formationUNITED States

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p47-55. 9p.

  • Abstract: Passive transfer of antibodies from COVID-19 convalescent patients is being used as an experimental treatment for eligible patients with

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Academic Journal

Associations Between Genetically Predicted Protein Levels and COVID-19 Severity.

Subjects: COVID-19; FALSE discovery rate; SARS-CoV-2

  • Source: Journal of Infectious Diseases. Jan2021, Vol. 223 Issue 1, p19-22. 4p.

  • Abstract: It is critical to identify potential causal targets for SARS-CoV-2, which may guide drug repurposing options. We assessed the associations between ...

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Academic Journal

A Granulocytic Signature Identifies COVID-19 and Its Severity.

Subjects: COVID-19; BIOMARKERS; INTENSIVE care units

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1985-1996. 12p.

  • Abstract: Background: An unbiased approach to SARS-CoV-2-induced immune dysregulation has not been undertaken so far. We aimed to identify ...

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Academic Journal

SARS-CoV-2 Antibody Avidity Responses in COVID-19 Patients and Convalescent Plasma Donors.

Subjects: CONVALESCENT plasma; COVID-19; SARS-CoV-2

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1974-1984. 11p.

  • Abstract: Background: Convalescent plasma therapy is a leading treatment for conferring temporary immunity to COVID-19-susceptible individuals or for use ...

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Academic Journal

COVID-19 Vaccines: Should We Fear ADE?

Subjects: COVID-19 vaccines; COVID-19; RESPIRATORY syncytial virus

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1946-1950. 5p.

  • Abstract: Might COVID-19 vaccines sensitize humans to antibody-dependent enhanced (ADE) breakthrough infections? This is unlikely because coronavirus diseases ...

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Academic Journal

Plasma From Recovered COVID-19 Patients Inhibits Spike Protein Binding to ACE2 in a Microsphere-Based Inhibition Assay.

Subjects: CARRIER proteins; COVID-19; ANGIOTENSIN converting enzyme

  • Source: Journal of Infectious Diseases. 12/15/2020, Vol. 222 Issue 12, p1965-1973. 9p.

  • Abstract: We present a microsphere-based flow cytometry assay that quantifies the ability of plasma to inhibit the binding of spike protein to angiotensin-converting enzyme 2. Plasma from 22 ...

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Academic Journal

Postmortem Findings in Italian Patients With COVID-19: A Descriptive Full Autopsy Study of Cases With and Without Comorbidities.

Subjects: COVID-19; AUTOPSY; POSTMORTEM changesROME

  • Source: Journal of Infectious Diseases. Dec2020, Vol. 222 Issue 11, p1807-1815. 9p.

  • Abstract: Background: Descriptions of the pathological features of coronavirus disease-2019 (COVID-19) caused by the novel zoonotic ...

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