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Academic Journal

Characteristics and transmission dynamics of COVID-19 in healthcare workers at a London teaching hospital

  • Source: In Journal of Hospital Infection October 2020 106(2):325-329

  • Abstract: Summary Background Healthcare worker (HCW)-associated coronavirus disease 2019 (COVID-19) is of global concern due to the potential ... Methods Staff records and virology testing results were combined to identify staff sickness and COVID-19 rates from March to April 2020. Comparisons ... Findings COVID-19 rates in our HCWs largely rose and declined in parallel with the number of community cases. White and non-White ... Conclusion Sustained transmission of SARS-CoV-2 among our hospital staff did not occur, beyond the community outbreak, even in the absence of ...

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Academic Journal

A novel cohorting and isolation strategy for suspected COVID-19 cases during a pandemic

  • Source: In Journal of Hospital Infection August 2020 105(4):632-637

  • Abstract: SUMMARY Background The COVID-19 pandemic presents a significant infection prevention and control challenge. The admission of large numbers of patients with ... Results Ninety-three patients were evaluated with 79 (85%) receiving a COVID-19 diagnosis during their admission. Of those without a COVID-19Discussion Application of a clinical triage tool to guide isolation and cohorting decisions may reduce the risk of hospital-acquired transmission of COVID-19

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Academic Journal

Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial Study (COVID in Older PEople)

  • Source: In Journal of Hospital Infection October 2020 106(2):376-384

  • Abstract: Summary Background Hospital admissions for non-coronavirus disease 2019 (COVID-19) pathology have decreased significantly. It is believed that ... Methods The COPE-Nosocomial Study was an observational cohort study. The primary outcome was the time to all-cause mortality (estimated with an adjusted hazard ratio (aHR)), ... Findings The study included 1564 patients from 10 hospital sites throughout the UK, and one in Italy, and collected outcomes on patients admitted up to April 28th, 2020. ... Conclusion The minority of COVID-19 cases were the result of NC transmission. No COVID-19 infection comes without ...

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Academic Journal

Incidence and outcomes of healthcare-associated COVID-19 infections: significance of delayed diagnosis and correlation with staff absence

  • Source: In Journal of Hospital Infection December 2020 106(4):663-672

  • Abstract: Summary Background The sudden increase in COVID-19 admissions in hospitals during the SARS-CoV-2 pandemic of 2020 led to ... Methods Electronic laboratory, patient and staff self-reported sickness records were interrogated from 1st March to 18th April 2020. HA-COVID-19 was defined ... Results Fifty-eight HA-COVID-19 (7.1%) cases were identified. When compared with community-acquired admitted cases (CA-COVID-19), significant differences ... Conclusions Early diagnosis and isolation of COVID-19 patients would help to reduce transmission. A single CTNS has limited value in segregating ...

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Academic Journal

Clinical characteristics and humoral immune response in healthcare workers with COVID-19 in a teaching hospital in Belgium

  • Source: In Journal of Hospital Infection December 2020 106(4):713-720

  • Abstract: Summary Background Healthcare workers (HCWs) are at high risk of acquiring COVID-19 and could play a role in nosocomial transmission. Since 4... Methods This retrospective study included 176 HCWs with laboratory-confirmed COVID-19 in a teaching hospital in Belgium. Between 1st March and 31st May 2020, ... Findings Median age was 40.8 years and 75% were female. Median delay between onset of symptoms and diagnosis was 4.39 days. Most frequent symptoms were cough and headache (... Conclusions Clinical presentation of COVID-19 in HCWs does not differ from the general population. However, outcomes were more favourable with a ...

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Academic Journal

Environmental contamination in the isolation rooms of COVID-19 patients with severe pneumonia requiring mechanical ventilation or high-flow oxygen therapy

  • Source: In Journal of Hospital Infection November 2020 106(3):570-576

  • Abstract: Summary Background Identifying the extent of environmental contamination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential ... Methods Environmental swab samples and air samples were collected from the isolation rooms of three COVID-19 patients with severe pneumonia. Patients 1 ... Findings Of the 48 swab samples collected in the rooms of patients 1 and 2, only samples from the outside surfaces of the endotracheal tubes tested positive for Conclusion Environmental contamination of SARS-CoV-2 may be a route of viral transmission. However, it might be minimized when patients receive mechanical ...

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Academic Journal

Super-factors associated with transmission of occupational COVID-19 infection among healthcare staff in Wuhan, China

  • Source: In Journal of Hospital Infection September 2020 106(1):25-34

  • Abstract: Summary Background Globally, there have been many cases of coronavirus disease 2019 (COVID-19) among medical staff; however, the ... Methods A cross-sectional study was conducted between January 1st and February 30th, 2020, in which front-line members of medical staff who took part in the care ... Findings A total of 92 medical staff were enrolled. In all participant groups, the super-factor identified by the network was wearing a medical protective mask or ... Conclusion High self-protection score was the main factor that prevented medical staff from contracting COVID-19 infection. The main factor contributing to

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Academic Journal

Disinfection of gloved hands during the COVID-19 pandemic

  • Source: In Journal of Hospital Infection January 2021 107:5-11

  • Abstract: Summary Background Disinfection of gloves can be used during a pandemic situation when performing various procedures on the same patient or when removing personal protective ... Methods One hundred percent powder-free nitrile gloves, composed of nitrile butadiene rubber compounds, were exposed to various disinfectants to analyse resistance. The seven most commonly ... Findings Bleach solution decreased the breaking load of gloves, although to a lesser extent than disinfectants that contained ethanol.Conclusion Disinfectants that contain alcohol decrease the breaking load of nitrile gloves.

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Academic Journal

In-hospital verification of non-CE-marked respiratory protective devices to ensure safety of healthcare staff during the COVID-19 outbreak

  • Source: In Journal of Hospital Infection July 2020 105(3):447-453

  • Abstract: Summary Background Due to the coronavirus disease 2019 (COVID-19) pandemic, a shortage of respirators is occurring worldwide; more ... Methods A protocol and criteria based on applicable standards were developed to ensure the quality of respirators. The protocol has been implemented at the Catharina ... Findings Sixty-seven percent of the respirator brands and types received in the Catharina Hospital did not meet quality criteria.Conclusion With a simple verification protocol the quality of the respirators can be checked and guaranteed while there is a shortage of the CE-approved respirators ...

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Academic Journal

N95 mask reuse in a major urban hospital: COVID-19 response process and procedure

  • Source: In Journal of Hospital Infection October 2020 106(2):277-282

  • Abstract: Summary Background The shortage of single-use N95 respirator masks (NRMs) during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2Methods NRM reusability was assessed following collection from volunteer staff after 2–8 h use, sterilization by autoclaving and PortaCount fit testing. A workflow was developed for ... Findings Used NRMs passed fit testing after autoclaving once, with 86% passing a second reuse/autoclave cycle. A separate cohort of used masks pre-warmed before autoclaving ... Conclusion Reuse of NRMs is feasible in major hospitals and other healthcare facilities. In sharp contrast to studies of unused NRMs passing fit testing after 10 ...

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