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Academic Journal

Iod povidona demonstrează activitate virucidă in vitro rapid instalată împotriva SARS-CoV-2, virusul responsabil de apariţia COVID-19.

Subjects: COVID-19; INFECTION control; RESPIRATORY infections

  • Source: Farmacist.ro; 2020, Issue 4, p31-35, 5p

  • Abstract: Introduction. As of 22 June 2020, Severe Acute Respiratory Syndrome (SARS)-coronavirus (CoV)-2 has infected more than 8.95 million people worldwide, causing >468,000 deaths. The virus is transmitted ... Introducere. La data de 22 iunie 2020, SARS-CoV-2, ce determină COVID-19, a infectat mai mult de 8,95 milioane de oameni din întreaga lume, determinând peste 468.000 de decese. ... Copyright of Farmacist.ro is the property of MEDICHUB MEDIA, S.R.L. and its content may not be copied or emailed to multiple ...

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Academic Journal

Iod povidona demonstrează activitate virucidă in vitro rapid instalată împotriva SARS-CoV-2, virusul responsabil de apariţia COVID-19.

Subjects: CORONAVIRUS diseases; COVID-19; SARS-CoV-2

  • Source: Medic.ro; 2020, Vol. 136 Issue 4, p30-34, 5p

  • Abstract: Introduction. As of 22 June 2020, Severe Acute Respiratory Syndrome (SARS)-coronavirus (CoV)-2 has infected more than 8.95 million people worldwide, causing >468,000 deaths. The virus is transmitted ... Introducere. La data de 22 iunie 2020, SARS- CoV-2, ce determină COVID-19, a infectat mai mult de 8,95 milioane de oameni din întreaga lume, determinând peste 468.000 de ... Copyright of Medic.ro is the property of MEDICHUB MEDIA, S.R.L. and its content may not be copied or emailed to multiple ...

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Academic Journal

Effects of CYP3A4 inducers with and without CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.

Subjects: PLACEBOS; CHEMOKINES; INTERFERON inducers

  • Source: British Journal of Clinical Pharmacology. Apr2008 Supplement 1, Vol. 65, p38-46. 9p. 1 Diagram, 5 Charts, 5 Graphs.

  • Abstract: AIMS To assess the potential of known CYP3A4 inducers, with and without CYP3A4 inhibitors, to alter the pharmacokinetic profile of maraviroc. METHODS Two ...

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Academic Journal

Population pharmacokinetic/ pharmacodynamic analysis of CCR5 receptor occupancy by maraviroc in healthy subjects and HIV-positive patients.

Subjects: HIV infections; THERAPEUTICS; PHARMACOKINETICS

  • Source: British Journal of Clinical Pharmacology. Apr2008 Supplement 1, Vol. 65, p86-94. 9p. 2 Charts, 5 Graphs.

  • Abstract: BACKGROUND Maraviroc, a noncompetitive antagonist of the CCR5 coreceptor, was recently approved in the USA as a treatment of HIV infection. For antiretroviral agents that ...

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Academic Journal

Three new structures of the core domain of HIV-1 integrase: An active site that binds magnesium.

Subjects: HIV; BIOLOGICAL mutation

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 08/04/98, Vol. 95 Issue 16, p9150, 5p, 7 Diagrams, 1 Chart

  • Abstract: Presents a study on the three additional crystal structures of the core domain of HIV-1 integrase mutants, crystallized in the presence and absence of cacodylate, ...

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Academic Journal

Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances...

Subjects: HIV; ZINC; PROTEINS

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 11/26/96, Vol. 93 Issue 24, p13659, 6p, 1 Diagram, 1 Chart, 5 Graphs

  • Abstract: Investigates the binding of zinc to HIV-1 integrase protein. Analysis of zinc binding to deletion derivatives of integrase; HIV-1 integrase's binding of zinc with a ...

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Academic Journal

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking.

Subjects: LYSINE; MUTAGENESIS; DNA viruses

  • Source: EMBO Journal; 11/15/97, Vol. 16 Issue 22, p6849-6859, 11p

  • Abstract: Analysis of the crystal structure of HIV-1 integrase reveals a cluster of lysine residues near the active site. Using site-directed mutagenesis and photo-crosslinking we find ... Copyright of EMBO Journal is the property of John Wiley & Sons, Inc. and its content may not be copied or emailed to multiple sites ...

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Academic Journal

DNA polymerase beta and DNA synthesis in Xenopus oocytes and in a nuclear extract.

Subjects: DNA

  • Source: Science. 10/16/1992, Vol. 258 Issue 5081, p475. 4p. 9 Black and White Photographs, 1 Graph.

  • Abstract: Examines the identities of the DNA polymerases required for conversion of single-strand (ss) M13 DNA to double-strand (ds) M13 DNA in injected Xenopus laevis oocytes ...

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  • 1-10 of  33 results for ""Jenkins, Timothy M.""